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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GAB1 All Species: 26.97
Human Site: Y373 Identified Species: 65.93
UniProt: Q13480 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13480 NP_002030.2 694 76616 Y373 A S D T D S S Y C I P T A G M
Chimpanzee Pan troglodytes XP_517458 724 80051 Y373 A S D T D S S Y C I P T A G M
Rhesus Macaque Macaca mulatta XP_001093044 724 80118 Y373 A S D T D N S Y C I P T A G M
Dog Lupus familis XP_540929 719 79343 Y368 A S D T D S S Y C I P T A G M
Cat Felis silvestris
Mouse Mus musculus Q9QYY0 695 76794 C374 S D T D S S Y C I P P P A G M
Rat Rattus norvegicus Q9EQH1 665 73310 E374 Q Q K P P I G E N S R S V A A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513247 815 89872 Y464 A S D T D N S Y C I P T A G V
Chicken Gallus gallus XP_420422 691 76488 Y370 A S D T D S S Y C I P T A G I
Frog Xenopus laevis NP_001089201 691 76011 Y369 V S E T D S N Y C V P T S G M
Zebra Danio Brachydanio rerio XP_692935 666 73590 R373 S T A S V I P R R N T L P A V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.3 94.8 90.2 N.A. 90.2 38.6 N.A. 76.9 88 75.5 40.2 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 95.5 95.1 92.3 N.A. 93.8 55.9 N.A. 80.6 92.5 85.4 56.2 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 93.3 100 N.A. 33.3 0 N.A. 86.6 93.3 66.6 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 40 6.6 N.A. 100 100 93.3 26.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 60 0 10 0 0 0 0 0 0 0 0 0 70 20 10 % A
% Cys: 0 0 0 0 0 0 0 10 70 0 0 0 0 0 0 % C
% Asp: 0 10 60 10 70 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 10 0 0 0 0 10 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 10 0 0 0 0 0 0 80 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 20 0 0 10 60 0 0 0 0 10 % I
% Lys: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 60 % M
% Asn: 0 0 0 0 0 20 10 0 10 10 0 0 0 0 0 % N
% Pro: 0 0 0 10 10 0 10 0 0 10 80 10 10 0 0 % P
% Gln: 10 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 10 10 0 10 0 0 0 0 % R
% Ser: 20 70 0 10 10 60 60 0 0 10 0 10 10 0 0 % S
% Thr: 0 10 10 70 0 0 0 0 0 0 10 70 0 0 0 % T
% Val: 10 0 0 0 10 0 0 0 0 10 0 0 10 0 20 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 10 70 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _